Humber College (HC), located in Toronto, Ontario, has been awarded with the NSERC Mobilize grant to strengthen regional partnerships and applied research (AR) capacity in Digital Transformation and Social Innovation and to build new capacity to help regional partners respond to the health, economic, and environmental crises brought about by the COVID-19 pandemic and climate change via two new interdisciplinary AR themes: Healthy Built Environments and the New World of Work. Our proposal also lays out our objectives and plans to provide comprehensive and impactful services to our partners and training experiences to develop HQP. In the long-term, Mobilize funding will enable Humber College to deepen capabilities to meet critical needs of our community, strategically grow opportunities to attract new partners and create more complex, multi-partnered initiatives with synergistic impacts, create impactful programs that engage underrepresented communities in research, and provide enhanced training to diverse HQP including students and emerging researchers (ER).